Wechsler subscale IQ and subtest profile in early treated phenylketonuria

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Wechsler subscale IQ and subtest profile in early treated phenylketonuria.

AIM Mildly depressed IQ is common in treated phenylketonuria. This study explored whether a particular intellectual ability profile typifies early and continuously treated phenylketonuria and whether component skills comprising the IQ relate to socioeconomic and treatment factors. METHODS IQ scores were collected retrospectively from variants of the "Wechsler intelligence scale for children" ...

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Executive function in early-treated phenylketonuria: profile and underlying mechanisms.

Despite early and continuous dietary intervention, individuals with early-treated phenylketonuria (PKU) experience significant neurocognitive sequelae. An area of cognitive ability that is believed to be particularly affected is executive function (EF). This paper provides a critical review of the evidence for EF impairment in early-treated PKU within the context of recent advances in neuropsyc...

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Diagnostic Validity of Wechsler Subtest Scatter

It has long been speculated that cognitive subtest scatter or variability is a pathognomonic sign. Early researchers hypothesized that subtest scatter would predict scholastic potential or membership in exceptional groups (Harris & Shakow, 1937). In fact, Binet suggested that scattered passes and failures on the Binet-Simon scale were diagnostically significant (Matarazzo, 1985), and Wechsler (...

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Problem-Solving Skills in Children with Early Treated Phenylketonuria

Objectives: This study aimed to investigate the level of problem-solving skills in 1-4 year-old children with early treated phenylketonuria (ETPKU). Methods:This analytic, cross-sectional study was conducted on 70 1-4 year-old children referred to phenylketonuria (PKU) clinics that had been diagnosed on screening at birth and had been treated. The measurements were a demographic questionnair...

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problem-solving skills in children with early treated phenylketonuria

objectives: this study aimed to investigate the level of problem-solving skills in 1-4 year-old children with early treated phenylketonuria (etpku). methods:this analytic, cross-sectional study was conducted on 70 1-4 year-old children referred to phenylketonuria (pku) clinics that had been diagnosed on screening at birth and had been treated. the measurements were a demographic questionnaire, ...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 2000

ISSN: 0003-9888

DOI: 10.1136/adc.82.3.209